Further evidence on the underestimation of the prevalence of TT viral DNA in blood donors We reassessed the prevalence of TT viral DNA in Italian blood donors by using primers derived from a highly conserved non-coding region
نویسنده
چکیده
study of hydroxyurea in sickle cell disease. French Study Group on Sickle Cell Disease. Arch Dis Child 1999; 81:437-9. 6. Kinney TR, Helms RW, O’Branski EE, et al. Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group. Blood 1999; 94:1550-4. 7. Wiger R, Hongslo JK, Evenson DP, De Angelis P, Schwarze PE, Holme JA. Effects of acetaminophen and hydroxyurea on spermatogenesis and sperm chromatin structure in laboratory mice. Reprod Toxicol 1995; 9:21-33.
منابع مشابه
Detection of the Frequency of the Novel TT virus by PCR and Its Role in the Induction of Hepatic Injuries in Blood Donors in West Azerbaijan, Iran
Background: In 1997, a novel DNA virus was isolated from the serum of a patient in Japan, and it was named TT virus (TTV). As the virus is replicated in liver and has the ability to induce apoptosis in hepatocytes (Hepatocellular carcinoma cells) it is hypothesized that TTV is an opportunistic virus and in certain conditions causes liver damage. In this study the frequency of infection with TTV...
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Abstract Background & aim: Occult hepatitis B virus infection in blood donors threats the safety of the blood supply. It is characterized by detection of low viral DNA in the serum subjects who have negative test for Hepatitis B surface antigen (HBsAg). The aim of this study was to assess the prevalence of occult hepatitis B virus infection among HBsAg negative and HBcAb positive in blood ...
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Abstract Background Increasing blood supply safety is one of the most important goals of blood services in the world. In this study, we reviewed the prevalence rate and the trends of three main infections in whole blood donations and strategies for improving blood safety in Yazd blood transfusion center, Iran. Materials and Methods In this cross sectional study, data on hepatitis B, C and ...
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Evaluation of trends in the rate of infectious diseases of blood donors is essential for monitoring safety of blood supply and effective screening of donors. Transfusion records of blood donors who attended the Center between 2002 and 2005 were reviewed for positive cases of HBS (by ELISA), HIV (by Western Blot) and HCV (by ELISA). During 2002–05, 507,531 persons donated blood. The prevalence r...
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Background and Aims: Occult hepatitis B virus infection (OBI) is known as an important source of hepatitis B virus (HBV) infection. It is categorized as Hepatitis B surface antigen (HBsAg) not being present and low DNA viral load in serum. In this study, an attempt was made to investigate the outbreak of anti-HBc and OBI among the HBsAg-negative donors in Golestan province. Materials and Metho...
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